ADOPTED_FROM:ISO/TS 10993-20:2006 <p>This part of <std><std-ref>ISO 10993</std-ref></std> presents an overview of immunotoxicology with particular reference to the potential immunotoxicity of medical devices. It gives guidance on methods for testing for immunotoxicity of various types of medical devices.</p><p>This part of <std><std-ref>ISO 10993</std-ref></std> is based on several publications written by various groups of immunotoxicologists over the last few decades in which the development of immunotoxicology as a separate entity within toxicology took place.</p><p>The current state of knowledge with regard to immunotoxicity is described in <xref ref-type="app" rid="sec_A">Annex A</xref>. A summary of clinical experience to date with immunotoxicology associated with medical devices is given in <xref ref-type="app" rid="sec_B">Annex B</xref>.</p><non-normative-note><label>NOTE</label><p>See also Bibliographic Reference <xref ref-type="bibr" rid="biblref_11">[11]</xref>.</p></non-normative-note>