Assessing the compatibility of materials and components in glazing systems is essential to ensuring the long-term performance of these systems. However, given the number and diversity of materials and components, it is challenging to test every possible combination against every conceivable factor. This document is intended to serve as a guideline to conduct performance testing on specific configurations, ultimately leading to more effective consideration of the factors involved in compatibility testing of glazing materials. This GIB is intended for glazing professionals or anyone with an interest in evaluating the compatibility of glazing materials and components. Note that even when compatibility is confirmed, in applications where adhesion of materials is critical for the performance of the glazing system, such adhesion must be verified independently.