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A study of the application of energy conservation principles in the design of a laboratory facility has been conducted at the Oak Ridge National Laboratory (ORNL). The principal objectives of this study were to evaluate the potential energy savings of alternative system designs, and to implement those alternatives which were economically feasible into the design of a new laboratory facility, the Environmental Sciences Laboratory Complex. A conceptual design report(l) for the complex had been prepared in 1972 by an architect-engineering firm and consequently was used as a basis for comparison in this study. The following is a discussion of the alternative design features that were examined and their relationship to annual energy usage.