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The two basic demands for air-conditioning and refrigeration products are higher efficiency and compact size. Past energy crises and recent international concerns about climate change or global warming potential (GWP) have garnered public attention on improving energy efficiency of airconditioning and refrigeration systems. In order to provide essential design information of microchannel evaporators, an experimental study was conducted on the effects of geometry, operating conditions and fluid properties on the distribution of refrigerant and pressure drops in horizontal heat exchanger manifolds. To achieve the proposed objective, an experimental facility with a visualization section for mimicking a real heat exchanger manifold geometry was developed.