When designing energy efficient buildings much attention is devoted to reducing building fabric, internal sensible heat loads and ventilation heat loads. Latent heat loads from people and ventilation are beginning to dominate our thinking toward satisfying our concepts of occupant comfort and mold control building wellness.The paper discusses the merits of split mass flow psychrometrics (SMFP) and cold cooling heat exchangers to disconnect the sensible and latent cooling processes. In association with SMFP, heat shifting within either air mass stream can provide further disconnection of the cold cooling process from the saturation curve to enhance occupant comfort management and control of the potential for mold growth within ducting systems.