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About This Item

 

Full Description

This Standard applies to Class II (laminar flow) biosafety cabinetry designed to minimize hazards inherent in work with agents assigned to biosafety levels 1, 2, 3, or 4. It also defines the tests that shall be passed by such cabinetry to meet this Standard. This Standard includes basic requirements for the design, construction, and performance of biosafety cabinets that are intended to provide personnel, product, and environmental protection; reliable operation; durability and structural stability; cleanability; limitations on noise level; illumination; vibration; and motor/blower performance.

This edition of the Standard (NSF/ANSI 49-2011) includes the following revisions:

Issue 27 - Class I and III
Updates to the Class I and III definitions in Section 3.

Issue 39 - Sound level and Adhesives
Updates to reflect OSHA guidelines for noise level readings in Section F.11.2 and also updates Section H.6.3 to reflect the IEST-RP-CC001 Section 8.3.2 recommendations for adhesives used in filter repair.

Issue 42 - Pressure decay test/Soap bubble leak test
Updates to the language in Annex F, section F.1.1.

Issue 43 - Canopy Requirements and Performance
Updates the language in 5.4 Canopy connect exhaust and in 5.25.4 Type A1 or A2 exhaust alarm to allow canopy testing for class II, type A1 & A2 cabinets. This same language is already part of Annex F (F.7.3.3).

 

Document History

  1. NSF/ANSI 49-2022


    Biosafety Cabinetry: Design, Construction, Performance, and Field Certification

    • Most Recent
  2. NSF/ANSI 49-2020


    Biosafety Cabinetry: Design, Construction, Performance, and Field Certification

    • Historical Version
  3. NSF/ANSI 49-2019


    Biosafety Cabinetry: Design, Construction, Performance, and Field Certification

    • Historical Version
  4. NSF 49-2018


    Biosafety Cabinetry: Design, Construction, Performance, and Field Certification

    • Historical Version
  5. NSF 49-2016


    Biosafety Cabinetry: Design, Construction, Performance, and Field Certification

    • Historical Version
  6. NSF 49-2014


    Biosafety Cabinetry: Design, Construction, Performance, and Field Certification

    • Historical Version
  7. NSF 49-2012

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    Biosafety Cabinetry: Design, Construction, Performance, and Field Certification

    • Historical Version
  8. NSF 49-2011


    Biosafety Cabinetry: Design, Construction, Performance, and Field Certification

    • Historical Version
  9. NSF 49-2010a


    Biosafety Cabinetry: Design, Construction, Performance, and Field Certification

    • Historical Version
  10. NSF 49-2009


    NSF 49 Class II (Laminar Flow) Biosafety Cabinetry

    • Historical Version
  11. NSF 49-2008


    NSF 49 Class II (Laminar Flow) Biosafety Cabinetry

    • Historical Version
  12. NSF 49-2007


    NSF 49 Class II (Laminar Flow) Biosafety Cabinetry

    • Historical Version
  13. NSF 49-2007 Annex F


    Class II (laminar flow) biosafety cabinetry -Field testing annex,Annex F to NSF/ANSI 49-2007

    • Historical Version
  14. NSF 49-2004a


    NSF 49 Class II (Laminar Flow) Biosafety Cabinetry

    • Historical Version
  15. NSF 49-04


    NSF 49 Class II (laminar flow) Biosafety Cabinetry

    • Historical Version
  16. NSF 49-2004 Annex F


    Class II (laminar flow) biosafety cabinetry -Field testing annex,Annex F to NSF/ANSI 49-04

    • Historical Version
  17. NSF 49-02e


    NSF 49 Class II (laminar flow) Biosafety Cabinetry

    • Historical Version
  18. NSF 49-2002 Annex F


    Class II (laminar flow) biosafety cabinetry -Field testing annex,Annex to NSF/ANSI 49-02

    • Historical Version
  19. NSF 49-2002


    Class II (Laminar Flow) Biohazard Cabinetry

    • Historical Version
  20. NSF 49-1992


    Class II (Laminar Flow) Biohazard Cabinetry

    • Historical Version