NSF 49-2011

This Standard applies to Class II (laminar flow) biosafety cabinetry designed to minimize hazards inherent in work with agents assigned to biosafety levels 1, 2, 3, or 4. It also defines the tests that shall be passed by such cabinetry to meet this Standard. This Standard includes basic requirements for the design, construction, and performance of biosafety cabinets that are intended to provide personnel, product, and environmental protection; reliable operation; durability and structural stability; cleanability; limitations on noise level; illumination; vibration; and motor/blower performance.

This edition of the Standard (NSF/ANSI 49-2011) includes the following revisions:

Issue 27 - Class I and III
Updates to the Class I and III definitions in Section 3.

Issue 39 - Sound level and Adhesives
Updates to reflect OSHA guidelines for noise level readings in Section F.11.2 and also updates Section H.6.3 to reflect the IEST-RP-CC001 Section 8.3.2 recommendations for adhesives used in filter repair.

Issue 42 - Pressure decay test/Soap bubble leak test
Updates to the language in Annex F, section F.1.1.

Issue 43 - Canopy Requirements and Performance
Updates the language in 5.4 Canopy connect exhaust and in 5.25.4 Type A1 or A2 exhaust alarm to allow canopy testing for class II, type A1 & A2 cabinets. This same language is already part of Annex F (F.7.3.3).