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Technical Guide 1001 launches the series of Guides, with general coverage of methods for sampling air in clean environments using a discrete-particle counter (DPC) to determine concentrations of airborne particles.The protocols presented are applicable for any cleanroom occupancy state and apply to classification (in accordance with ISO 14644-1), as well as monitoring (in accordance with ISO 14644-2). Several terms specific to counting procedures are defined. This document also provides detailed setup procedures to complement the concise provisions of section B.4.3 of ISO 14644-1.