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This paper presents the key conclusions from an extensive research project on ventilation design in animal research facilities using static microisolators. This study, which is presented in full in Memarzadeh (1998), considered both experimental and numerical aspects using the computational fluid dynamics (CFD) technique. As well as a summary of various gaseous generation rates for mice, this paper contains conclusions on the effects of changing various parameters within an animal research room on conditions in the cages and in the main room volume itself. These parameters include, but are not limited to, supply type, exhaust location and number, room ventilation rate, and supply air temperature and moisture content.

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