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About This Item

 

Full Description

1.1 This practice covers a nonspecific, acute toxicity test used for detecting leachables from materials used in medical devices.

1.2 The liquids injected in the mouse are those obtained by Practice F 619 where the extraction vehicles are saline, vegetable oil, or other liquids simulating human body fluids.

1.3 Two procedures are outlined: Method A for intravenous injection and Method B for intraperitoneal injection.

1.4 This practice is one of several developed for the assessment of the biocompatibility of materials. Practice F 748 may provide guidance for the selection of appropriate methods for testing materials for a specific application.

 

Document History

  1. ASTM F750-20


    Standard Practice for Evaluating Acute Systemic Toxicity of Material Extracts by Systemic Injection in the Mouse

    • Most Recent
  2. ASTM F750-87(2012)


    Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse

    • Historical Version
  3. ASTM F750-87(2007)e1


    Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse

    • Historical Version
  4. ASTM F750-87(2007)


    Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse

    • Historical Version
  5. ASTM F750-87(2002)e1


    Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse

    • Historical Version
  6. ASTM F750-87(2002)


    Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse

    • Historical Version
  7. ASTM F750-87(1996)

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    Standard Practice for Evaluating Material Extracts by Systemic Injection in the Mouse

    • Historical Version