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This paper describes the partial implementation of a novel method of controlling indoor air quality (IAQ) for critical applications. The proposed method uses a numerical modeling technique known as computational fluid dynamics (CFD) for modeling the effect of variable ventilation rates for intelligent and rapid control of air contamination in space. This paper describes how a CFD model is made to run in real time linked to a feedback control loop. The technique was simulated in a graphical programming language. The simulation results indicate that a quasi-transient potential flow CFD model is a viable technique for feedback control of IAQ, and it is currently being implemented in an experimental validation.