This standard applies to the selection of an appropriate cylinder valve outlet connection for medical gases for pressures up to 3000 psi (20 680 kPa) at 70 °F (21.1 °C). It does not apply to industrial gas mixtures, cylinders manifolded in transport and use, or to mixtures at higher pressures. Both threaded and pin-indexed connection assignments are included with reference to CGA V-1, Standard for Compressed Gas Cylinder Valve Outlet and Inlet Connections.

This revision replaces the use of limited standards with alternate standards for the purpose of assuring only one connection assignment will be appropriate. This revision brings consistency with ISO 407:2004, Small medical gas cylinders—Pin-index yoke-type valve connections, to standardize pin-indexed yoke-type valve connections globally.

The purpose of this standard is to establish a procedure for selecting the appropriate cylinder valve outlet connection for medical gases. It does not attempt to identify which medical gases may be safely manufactured nor indicate that the connection is safe or effective for any medical procedure. It is the responsibility of the manufacturer, the medical community, and appropriate regulatory bodies to make those decisions.