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This article describes the removal of natural organic matter (NOM) from water by a combined adsorption-membrane filtration process as compared with removal by enhanced coagulation. The authors describe how the heated iron oxide particle-ultrafiltration (HIOP-UF) process that had been tested using a single hollow-fiber membrane was investigated at a larger scale for different water sources, and the feasibility of on-site regeneration and reuse of the HIOPs was explored. The study was conducted in two phases. The first phase established appropriate operating conditions for both water treatment and HIOP regeneration, and the system's treatment of three natural water sources was evaluated. Reduction in dissolved organic carbon (DOC), UV absorbance, and trihalomethane formation potential (THMFP) were monitored along with transmembrane pressure differential required to maintain a constant permeate flux (as a measure of membrane fouling). The second phase evaluated how well the process treated water sources of different quality from 13 utilities. DOC removal from most of these water sources by enhanced coagulation was reported, providing a point of comparison between the HIOP-UF process and more conventional DOC removal processes. Erratum -- A number of errors occurred in this article: in figure 6, the symbols for "UF only" and "HIOP-UF, ambient pH" were reversed in the legend; and, the caption for Figure 9 should have read "DOC removal by the HIOP-UF process (100 mg/L Fe) for waters of various pH and SUVA 254." Includes 13 references, tables, figures.