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Clinical and Laboratory Standards Institute document GP15-A3--Cervicovaginal Cytology Based on the Papanicolaou Technique; Approved Guideline--Third Edition is intended for health care providers who are responsible for collecting cervicovaginal cytology specimens and preparing conventional Papanicolaou smears and liquid-based preparations. The guideline focuses on quality collection and processing of specimens, addressing all steps, including patient assessment, test requisition, specimen collection, specimen transport, and specimen receipt and processing. Illustrations of the techniques are described, and a specimen requisition form is also included.